Dr. Jean Bosco MUNYEMANA

Academic rank: 
Email: 
j.b.munyemana@ur.ac.rw
Telephone: 
+250788226375
Published Papers : 

1. Munyemana JB, Kabayiza JC, Nilsson S, Andersson ME, Lindh M. Shigella and Enterotoxigenic Escherichia coli Have Replaced Rotavirus as Main Causes of Childhood Diarrhea in Rwanda After 10 Years of Rotavirus Vaccination. J Infect Dis. 2024 Nov 15;230(5):e1176-e1180. doi: 10.1093/infdis/jiae446. PMID: 39248312; PMCID: PMC11566240.
2. Munyemana JB, Kabayiza JC, Seruyange E, Nilsson S, Rydell GE, Martner A, Andersson ME, Lindh M. Non-Secretor Status Due to FUT2 Stop Mutation Is Associated with Reduced Rotavirus Infections but Not with Other Enteric Pathogens in Rwandan Children. Microorganisms. 2025 May 3;13(5):1071. doi: 10.3390/microorganisms13051071. PMID: 40431244; PMCID: PMC12114204.
3. Munyemana JB, Kabayiza JC, Seruyange E, Nilsson S, Andersson ME, Lindh M. Acquisition and clearance of enteric pathogens in children under 5 years of age in Kigali and Musanze, Rwanda, 2022: a longitudinal cohort study. Clin Microbiol Infect. 2025 Jun 21:S1198-743X(25)00305-2. doi: 10.1016/j.cmi.2025.06.018. Epub ahead of print. PMID: 40550361.
4. Bikoroti JB, Mukambasabire B, Uwizeyimana G, Munyemana JB, Mariza J. Antimicrobial Resistance in Surgical Patients at the University Teaching Hospital of Kigali: A Cross-Sectional Study. Am J Trop Med Hyg. 2025 Apr 1:tpmd240740. doi: 10.4269/ajtmh.24-0740. Epub ahead of print. PMID: 40168981.
5. Mbabazi E, Munyemana JB, Mukashema J, Bazimaziki E, Ndayisaba MC, Adegboyega TT, Rugwizangoga B. Prevalence of Human Papillomavirus and Genotype Correlation with Cervical Lesions at the University Teaching Hospital of Kigali. Am J Trop Med Hyg. 2025 Mar 25:tpmd240760. doi: 10.4269/ajtmh.24-0760. Epub ahead of print. PMID: 40132222.
6. Mukabizimana J, Kayiranga D, Katende G, Munyemana JB. Evaluating practices toward dental health among primary school children in Rwanda. BMC Oral Health. 2024 Nov 24;24(1):1433. doi: 10.1186/s12903-024-05225-2. PMID: 39581980.
7. Gashegu, M., Gahamanyi, N., Ndayambaje, F. X., Munyemana, J. B., Ndahindwa, V., Lukwago, F., Ingabire, L., Gambanga, F., Gashema, P., Tuyishime, A., Dzinamarira, T., Dukundane, D., Muvunyi, T. Z., & Muvunyi, C. M. Exploring Prescription Practices: Insights from an Antimicrobial Stewardship Program at a Tertiary Healthcare Facility, Rwanda. Antibiotics, 13(6), 548. https://doi.org/10.3390/antibiotics13060548
8. Munyemana JB, Gatare B, Kabanyana P, Ivang A, Mbarushimana D, Itangishaka I, Niringiyumukiza JD, Musoni E. Antimicrobial Resistance Profile of Bacteria Causing Pediatric Infections at the University Teaching Hospital in Rwanda. Am J Trop Med Hyg. 2022 Oct 10;107(6):1308-1314. doi: 10.4269/ajtmh.22-0047. PMID: 36216320; PMCID: PMC9768258.
9. Ngangali JP, Mutesa L, Nsanzimana S, Munyemana JB, Injera EW, Kirtika P, et al. (2021) The Interleukin-6 and Interleukin-10 Plasma Levels the Driver of Immune Dysfunction and Chronic Inflammation in HIV Infection. J Infect Dis Prev Med. : 248.
10. Munyemana JB, Mukanoheli E, Nsabimana T, Niringiyumukiza JD. HCV Seroprevalence among HIV Patients and Associated Comorbidities at One Primary Health Facility in Rwanda. Am J Trop Med Hyg. 2021 Mar 15;104(5):1747-1750. doi: 10.4269/ajtmh.20-0500. PMID: 33720846; PMCID: PMC8103456.
11. Bosco, M. J., Jonas, B., Evelyne, K., & Pauline, K. (2020). Urinary tract infection and antimicrobial resistance profile in patients attending Nemba District Hospital in Rwanda. Asian Journal of Medical Sciences, 11(6), 101–105. https://doi.org/10.3126/ajms.v11i6.29921
12. Wu X, Huang H, Hou H, Shen G, Yu J, Zhou Y, Bosco MJ, Mao L, Wang F, Sun Z. Diagnostic Performance of a 5-Marker Predictive Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease. Inflamm Bowel Dis. 2018 Oct 12;24(11):2452-2460. doi: 10.1093/ibd/izy154. PMID: 29860270.
13. Jean Bosco M, Wei M, Hou H, Yu J, Lin Q, Luo Y, Sun Z, Wang F. The exhausted CD4+CXCR5+ T cells involve the pathogenesis of human tuberculosis disease. Int J Infect Dis. 2018 Sep;74:1-9. doi: 10.1016/j.ijid.2018.06.011. Epub 2018 Jun 21. PMID: 29936320.
14. Hou H, Zhou Y, Yu J, Mao L, Bosco MJ, Wang J, Lu Y, Mao L, Wu X, Wang F, Sun Z. Establishment of the Reference Intervals of Lymphocyte Function in Healthy Adults Based on IFN-γ Secretion Assay upon Phorbol-12-Myristate-13-Acetate/Ionomycin Stimulation. Front Immunol. 2018 Feb 7;9:172. doi: 10.3389/fimmu.2018.00172. PMID: 29467761; PMCID: PMC5808316.
15. Bosco MJ, Hou H, Mao L, Wu X, Ramroop KD, Lu Y, Mao L, Zhou Y, Sun Z, Wang F. The performance of the TBAg/PHA ratio in the diagnosis of active TB disease in immunocompromised patients. Int J Infect Dis. 2017 Jun;59:55-60. doi: 10.1016/j.ijid.2017.03.025. Epub 2017 Apr 7. PMID: 28392318.
16. Mao L, Hou H, Wu S, Zhou Y, Wang J, Yu J, Wu X, Lu Y, Mao L, Bosco MJ, Wang F, Sun Z. TIGIT signalling pathway negatively regulates CD4+ T-cell responses in systemic lupus erythematosus. Immunology. 2017 Jul;151(3):280-290. doi: 10.1111/imm.12715. Epub 2017 Feb 20. PMID: 28108989; PMCID: PMC5461105.
17. Munymana JB, M'kumbuzi VR, Mapira HT, Nzabanterura I, Uwamariyai I, Shema E. Prevalence of HIV among people with physical disabilities in Rwanda. Cent Afr J Med. 2014 Sep-Dec;60(9-12):62-9. PMID: 26867257.
18. Munyemana JB, Uwizeyimana G, Ndayisaba MC, Dusabe A, Mutsaka-Makuvaza MJ, Sinumvayo JP, Kantarama E, Rubambana N, Mwiseneza L, Hahirwa I, Rugwizangoga B, Masaisa F, Nyundo M, Mpunga T. Five-year surveillance of antimicrobial resistance patterns among blood culture isolates at the University Teaching Hospital, Kigali, Rwanda. Ann Clin Microbiol Antimicrob. 2025 Dec 2. doi: 10.1186/s12941-025-00837-0. Epub ahead of print. PMID: 41331622.

Brief profile: 
Dr. Jean Bosco Munyemana holds a PhD in Infectious Diseases and a Master of Medicine (MMed) in Clinical Microbiology and Immunology. He is a Clinical Microbiologist at the University Teaching Hospital of Kigali (CHUK) and a faculty member at the University of Rwanda, College of Medicine and Health Sciences, Department of Microbiology and Parasitology. His research focuses on tropical infectious diseases, antimicrobial resistance, and host immunity. Dr Jean Bosco has received or participated in 4 different grants, supervised more than 10 students, including 3 Master’s, and published around 20 articles, which can be accessed on his ResearchGate: ResearchGate Link
Research Area: 
Infectious Diseases, Antimicrobial resistance (AMR), and Immunity. Research ID (ORCID): 0000-0003-2547-8070