Semukunzi Herve

Academic rank: 
Email: 
h.semukunzi@ur.ac.rw
Telephone: 
+250788574513
Twitter: 
@hervesem
Department: 
Published Papers : 

1. Li H, Sun L, De Carvalho E L, Li X, Lv X, Khan GJ, Semukunzi H, Yuan S, Lin S. DT-13, a saponin monomer of dwarf lilyturf tuber, induces autophagy and potentiates anti-cancer effect of nutrient deprivation [J]. European journal of pharmacology, 2016, 781:164-172.
•    DOI:  10.1016/j.ejphar.2016.04.016. (SDG 3: Good Health and Well-being)
2. Roy D, Sheng G Y, Herve S, Semukunzi H, Li H, Lin S. Interplay between cancer cell cycle and metabolism: Challenges, targets and therapeutic opportunities [J]. Biomedicine & pharmacotherapy, 2017, 89:288-296.
•    DOI:  10.1016/j.biopha.2017.01.019. (SDG 3: Good Health and Well-being)
3. Semukunzi H, Roy D, Li H, Lin S. IDH mutations associated impact on related cancer epidemiology and subsequent effect toward HIF-1alpha [J]. Biomedicine & pharmacotherapy, 2017, 89:805-811.
•    DOI:  10.1016/j.biopha.2017.02.083. (SDG 3: Good Health and Well-being)
4. Li H, Sun L, Li H, Lv X, Semukunzi H, Li R, Yu J, Yuan S, Lin S. DT-13, a saponin monomer 13 of the Dwarf lilyturf tuber, synergized with vinorelbine to induce mitotic arrest via activation of ERK signaling pathway in NCI-H1299 cells [J]. Biomedicine & pharmacotherapy, 2017, 89:1277-1285.
•    DOI:  10.1016/j.biopha.2017.02.104. (SDG 3: Good Health and Well-being)
5. Khan GJ, Gao Y, Gu M, Wang L, Khan S, Naeem F, Yousef BA, Roy D, Semukunzi H, Yuan S, Sun L. TGF-β1 Causes EMT by regulating N-Acetyl Glucosaminyl Transferases via Downregulation of Non Muscle Myosin II-A through JNK/P38/PI3K pathway in lung cancer [J]. Current Cancer Drug Targets, 2017.
•    DOI:  10.2174/1568009617666170807120304. (SDG 3: Good Health and Well-being)

Brief profile: 
I am an academic, Assistant Lecturer at the University of Rwanda in CMHS/SoMP where I assist in teaching subjects related to pharmacodynamics, especially drug screening, and cardiovascular systems. I am a Junior Consultant in Pharmacy, registered in Rwanda. I am a cold chain supply trainer for EPI (Expanded Immunization Program) in the RCE EAC VIHSCM (Regional Center of Excellence for East African Community Vaccine, Immunization, and Health Supply Chain Management), and a hospital supply chain pharmacist at the University Teaching Hospital of Butare. I am currently a PhD Candidate working in both the Department of Chemical Engineering and The Clinical Immunology Services Department at the University of Birmingham. My interests are vast, but I have worked in infectious diseases in the past and have helped implement theAntimicrobial Stewardship (AMS) program where myself and colleagues were working on behavioral change in resource-limited settings through AMS reviews. My Msc research was on cancer related drug discovery, especially pathways, my PhD research is on the “Development of novel immune diagnostics for vaccine prioritization in low-to-middle income (LMIC) settings”, which will drive an efficient improvement in the implementation and assessment of vaccination in LMICs
Research Area: 
Vaccinology and pharmacodynamics/ signaling pathways. Research ID (ORCID): https://orcid.org/0000-0002-4968-8024