Dr. Fentahun Adane Nigat

Academic rank: 
Academic Leadership Position: 
PhD by research in anatomy program director
Email: 
a.fentahun@ur.ac.rw
Telephone: 
2.50797E+11
Published Papers : 
1. Sub-chronic toxicity of the aqueous leaf extract of Ocimum lamiifolium Hochst. ex Benth on biochemical parameters and histopathology of liver and kidney in rats: in vivo and in- silico toxicity studies
BMC Complementary Medicine and Therapies
2023-02-02 | Journal article
DOI: 10.1186/s12906-023-03863-7
Part of ISSN: 2662-7671
Contributors: Fentahun Adane; Wubshet Assefa; Mamaru Bitew Alem; Megbar Dessalegn
2. Composition of the Essential Oil Thymus schimperi and Evaluation of Its Acute and Subacute Toxicity in Wistar Albino Rats: In Silico Toxicity Studies
Evidence-Based Complementary and Alternative Medicine
2021-07-23 | Journal article
DOI: 10.1155/2021/5521302
Contributors: Fentahun Adane; Kaleab Asres; Wondwossen Ergete; Samuel Woldekidan; Abiy Abebe; Boki Lengiso; Girma Seyoum; Muhammad Nabeel Ghayur
3. The Developmental Toxicity of Thymus schimperi Essential Oil in Rat Embryos and Fetuses
Journal of Toxicology
2022-04-11 | Journal article
DOI: 10.1155/2022/4091839
Contributors: Fentahun Adane; Kaleab Asres; Wondwossen Ergete; Samuel Woldekidan; Girma Seyoum; Orish Ebere Orisakwe
4. In silico Screening of Potential SARS-CoV-2 Main Protease Inhibitors from Thymus schimperi
Advances and Applications in Bioinformatics and Chemistry
2023-01 | Journal article
DOI: 10.2147/AABC.S393084
Contributors: Hylemariam Mihiretie Mengist; Zunera Khalid; Fentahun Adane
5. Roles of cardiac neural crest cells in cardiovascular development and associated congenital defects-an integrated review
Translational Research in Anatomy
2024-09 | Journal article
Contributors: Fentahun Adane
6. Bacterial profle, antimicrobial susceptibility patterns, and associated factors among lower respiratory tract infection patients attending at Debre Markos comprehensive specialized hospital, Northwest, Ethiopia
Homepage URL: https://doi.org/10.1186/s12879-025-10633-y
BMC Infectious Diseases
2025-02-24 | Journal article
Contributors: Fentahun Adane
7. Prolonged length of stay and associated factors among emergency department patients in Ethiopia: systematic review and meta-analysis
BMC Emergency Medicine
2024-11-13 | Journal article
Contributors: Fentahun Adane
Homepage URL: https://doi.org/10.1186/s12873-024-01131-6
8. Vitamin D deficiency and its associated factors among patients with type 2 diabetes mellitus: a systematic review and meta-analysis
BMJ Open
2023-10 | Journal article
DOI: 10.1136/bmjopen-2023-075607
Part of ISSN: 2044-6055
Part of ISSN: 2044-6055
Contributors: Mitku Mammo Taderegew; Gashaw Garedew Woldeamanuel; Alemayehu Wondie; Atsede Getawey; Abera Nesiru Abegaz; Fentahun Adane
9. Magnitude and predictors of unfavorable management outcome in surgically treated patients with intestinal obstruction in Ethiopia: a systematic review and meta-analysis
BMC Surgery
2023-05-16 | Journal article
DOI: 10.1186/s12893-023-02017-3
Part of ISSN: 1471-2482
Contributors: Fentahun Adane; Megbar Dessalegn
10. Computer vision syndrome and predictors among computer users in Ethiopia: a systematic review and meta-analysis
Tropical Medicine and Health
2022-12 | Journal article
DOI: 10.1186/s41182-022-00418-3
Contributors: Fentahun Adane; Yoseph Merkeb Alamneh; Melaku Desta
11. Non-prescribed drug use and predictors among pregnant women in Ethiopia: systematic review and meta-analysis
The Journal of Maternal-Fetal & Neonatal Medicine
2022-11-17 | Journal article
DOI: 10.1080/14767058.2020.1849105
Contributors: Fentahun Adane; Girma Seyoum; Yoseph Merkeb Alamneh
12. Diabetes mellitus and its associated risk factors in patients with human immunodeficiency virus on anti-retroviral therapy at referral hospitals of Northwest Ethiopia
Diabetology and Metabolic Syndrome
2020 | Journal article
DOI: 10.1186/s13098-020-00527-1
EID: 2-s2.0-85081229277
Part of ISBN: 17585996
Contributors: Gebrie, A.; Tesfaye, B.; Gebru, T.; Adane, F.; Abie, W.; Sisay, M.
13. Essential newborn care utilization and associated factors in Ethiopia: A systematic review and meta-Analysis
BMC Pregnancy and Childbirth
2020 | Journal article
DOI: 10.1186/s12884-020-2804-7
EID: 2-s2.0-85080963495
Part of ISBN: 14712393
Contributors: Alamneh, Y.; Adane, F.; Yirga, T.; Desta, M.
14. Herbal medicine use and predictors among pregnant women attending antenatal care in Ethiopia: A systematic review and meta-analysis
BMC Pregnancy and Childbirth
2020 | Journal article
DOI: 10.1186/s12884-020-2856-8
EID: 2-s2.0-85081659169
Part of ISBN: 14712393
Contributors: Adane, F.; Seyoum, G.; Alamneh, Y.M.; Abie, W.; Desta, M.; Sisay, B.
15. Prevalence and associated factors of birth defects among newborns in sub-Saharan African countries: a systematic review and meta-analysis
Pan African Medical Journal
2020 | Journal article
DOI: 10.11604/pamj.2020.36.19.19411
Part of ISSN: 1937-8688
16. Prevalence and predictors of uterine rupture among Ethiopian women: A systematic review and meta-analysis
PLOS ONE
2020-11-02 | Journal article
DOI: 10.1371/journal.pone.0240675
Contributors: Melaku Desta; Gizachew Tessema; Haile Amha; Keralem Anteneh Bishaw; Fentahun Adane; Moges Agazhe Assemie; Getiye Dejenu Kibret; Nigus Bililign Yimer
17. Magnitude and Predictors of Pneumonia among Under-Five Children in Ethiopia: A Systematic Review and Meta-Analysis
Journal of Environmental and Public Health
2020-05-30 | Journal article
DOI: 10.1155/2020/1606783
Contributors: Yoseph Merkeb Alamneh; Fentahun Adane
18. Prevalence and root causes of surgical site infection among women undergoing caesarean section in Ethiopia: A systematic review and meta-analysis
Patient Safety in Surgery
2019 | Journal article
DOI: 10.1186/s13037-019-0212-6
EID: 2-s2.0-85074515256
Part of ISBN: 17549493
Contributors: Adane, F.; Mulu, A.; Seyoum, G.; Gebrie, A.; Lake, A.
19. Prevalence and associated factors of birth defects among newborns at referral hospitals in Northwest Ethiopia
Ethiopian Journal of Health Development
2018 | Journal article
EID: 2-s2.0-85057354552
Part of ISBN: 10216790
Contributors: Adane, F.; Seyoum, G.
20. Prevalence and determinants of antenatal depression among pregnant women in Ethiopia: A systematic review and meta-analysis 11 Medical and Health Sciences 1117 Public Health and Health Services
BMC Pregnancy and Childbirth
2018 | Journal article
DOI: 10.1186/s12884-018-2101-x
EID: 2-s2.0-85057522940
Part of ISBN: 14712393
Contributors: Zegeye, A.; Alebel, A.; Gebrie, A.; Tesfaye, B.; Belay, Y.A.; Adane, F.; Abie, W.
21. Cervical cancer screening utilization and predictors among eligible women in Ethiopia: A systematic review and meta-analysis
Homepage URL
https://doi.org/10.1371/journal.pone.0259339
22. Computer vision syndrome and associated factors among computer users in Debre Tabor Town, Northwest Ethiopia
https://doi.org/10.1155/2018/4107590
23. Diabetic dyslipidaemia and its determinants among people with diabetes in South Africa: a systematic review and meta-analysis protocol
DOI:10.2196/82716
URL: https://preprints.jmir.org/preprint/82716
24. Diabetic dyslipidaemia and its predictors among hyperglycaemic patients in South Africa: systematic review and meta-analysis. Eurasian Journal of Medicine and Oncology. 2025; Epub ahead of print.
Manuscript ID: EJMO025380402.
Brief profile: 
"Dr. Fentahun Adane Nigat is a Senior Lecturer in Human Anatomy at the School of Medicine, College of Medicine and Health Sciences, University of Rwanda. He holds a BSc, and MSc and PhD degrees in Human Anatomy. He is a former Arturo Falaschi Postdoctoral Fellow at the International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi. Dr. Adane’s research focuses on atherosclerosis and cardiovascular disease, with particular emphasis on LOX-1–mediated mechanisms, preclinical drug discovery, and translational biomarkers. His expertise includes in vivo and in vitro experimental models, toxicological evaluation using rodent models, platelet biology, and advanced murine models of atherosclerosis. He also has research interests in developmental anatomy and birth defects. He has published in peer-reviewed journals and is actively involved in postgraduate teaching, mentorship, and collaborative research aimed at improving cardiovascular health in African and global populations."
Research Area: 
My research focuses on atherosclerosis and cardiovascular disease, integrating epidemiology, systematic reviews and meta-analyses, and translational preclinical research. My work also includes toxicological evaluations using rat models (acute and sub-acute toxicity studies) and research on birth defects and developmental abnormalities, with emphasis on underlying mechanisms, risk factors, and translational relevance to human health. Research ID number (ORCID): 0000-0001-6490-0743